State police fire marshals and trying to determine the cause of the blaze.

ASHLAND, Pa. (AP) – Authorities say a woman and her teenage brother were killed in a fire that destroyed an eastern Pennsylvania home, also injuring two other relatives.

Officials in Schuylkill County said the blaze was reported at about 12:30 a.m. Friday in the Butler Township residence.

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Fire officials said crews arrived to find that the structure had collapsed and were unable to reach the victims.

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Chief Edward Tarantelli of the township police force said the bodies of 29-year-old Alison Marie Houser and her 13-year-old brother, Andrew John “A.J.” Charriez, 13, were found later.

State police fire marshals and trying to determine the cause of the blaze.

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